Vance signals growing gaps with Israel on Iran strategy

US Vice President JD Vance acknowledged that Washington and Jerusalem do not always share the same priorities on Iran, making clear that the Trump administration will pursue what it believes is best for America — even if Israel disagrees.

Speaking to Fox News, Vance stressed that while the United States and Israel have a close alliance and many shared interests, Washington’s primary objective is preventing Iran from obtaining a nuclear weapon through a long-term agreement. “Israel may like that, they may not like that,” he said, emphasizing that US policy will be guided by American national interests.

The comments come as President Donald Trump remains optimistic about the diplomatic track, predicting a “total victory” over Iran within weeks and expressing confidence that Tehran is moving closer to accepting key American demands. Trump has repeatedly insisted that Iran’s highly enriched uranium must be removed and that the regime will never be allowed to acquire nuclear weapons.

However, Iranian officials have painted a very different picture, claiming negotiations have reached a deadlock and placing the responsibility for any breakthrough squarely on Washington. The contrasting messages underscore growing uncertainty over whether diplomacy can succeed — and highlight emerging tensions between the White House and Israel over how to confront the Iranian regime.